Limonene

Category: Scientific · Level: Expert

Limonene is a cannabis terpene with a citrus aroma, studied for potential anti-anxiety, antidepressant, and anti-cancer properties.

Limonene is a cyclic monoterpene and one of the most common terpenes in cannabis and citrus fruits. It is responsible for bright, citrusy aromas in many popular cultivars. Beyond aroma, limonene has been studied for potential therapeutic properties including anxiolytic, antidepressant, anti-inflammatory, and anti-tumor activities in preclinical models. Limonene is used extensively in the food, fragrance, and pharmaceutical industries. In cannabis pharmacology, it is proposed to modulate the activity of THC and other cannabinoids as part of the entourage effect. Some research suggests limonene may inhibit growth of certain cancer cell lines, though human clinical data is limited.

Also known as

D-limonene, Citrus terpene

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